Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR5A | P47898 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035071 | 1.00 | GHSR (0.46) | GHSRMEN1KMT2AKCNH2MCHR1 | |
| SCHEMBL21035344 | 1.00 | GHSR (0.46) | GHSRMEN1KMT2AKCNH2MCHR1 | |
| SCHEMBL21002018 | 0.90 | GHSR (0.40) | GHSRMEN1KMT2AKCNH2MCHR1 | |
| SCHEMBL21036182 | 0.90 | GHSR (0.40) | GHSRMEN1KMT2AKCNH2MCHR1 | |
| SCHEMBL21034962 | 0.90 | GHSR (0.40) | GHSRMEN1KMT2AKCNH2MCHR1 | |
| SCHEMBL21036183 | 0.90 | GHSR (0.40) | GHSRMEN1KMT2AKCNH2MCHR1 | |
| SCHEMBL21034966 | 0.90 | GHSR (0.40) | GHSRMEN1KMT2AKCNH2MCHR1 | |
| SCHEMBL21036231 | 0.90 | CHEK2 (0.40) | GHSRKCNH2MCHR1CHEK2HTR1A | |
| SCHEMBL21036187 | 0.90 | CHEK2 (0.40) | GHSRKCNH2MCHR1CHEK2HTR1A | |
| SCHEMBL21035094 | 0.90 | CHEK2 (0.40) | GHSRKCNH2MCHR1CHEK2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |