Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035443 | 1.00 | GHSR (0.47) | GHSRMEN1KMT2AMMP1MMP3 | |
| SCHEMBL21035601 | 1.00 | GHSR (0.47) | GHSRMEN1KMT2AMMP1MMP3 | |
| SCHEMBL21036206 | 0.94 | MEN1 (0.45) | GHSRMEN1KMT2AMMP1MMP3 | |
| SCHEMBL21035327 | 0.94 | MEN1 (0.45) | GHSRMEN1KMT2AMMP1MMP3 | |
| SCHEMBL21034954 | 0.94 | MEN1 (0.45) | GHSRMEN1KMT2AMMP1MMP3 | |
| SCHEMBL21036230 | 0.94 | GHSR (0.44) | GHSRMEN1KMT2AMMP1MMP3 | |
| SCHEMBL21034943 | 0.93 | GHSR (0.47) | GHSRMMP1MMP3MMP7MMP9 | |
| SCHEMBL21035091 | 0.93 | GHSR (0.44) | GHSRMEN1KMT2AMMP1MMP3 | |
| SCHEMBL21035089 | 0.92 | GHSR (0.45) | GHSRMEN1KMT2AMMP1MMP3 | |
| SCHEMBL21002184 | 0.91 | MEN1 (0.43) | GHSRMEN1KMT2AMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |