Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 4/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680170 | 0.86 | HTR2C (0.50) | SRD5A1PNMTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL3682570 | 0.79 | SRD5A1 (0.49) | SRD5A1PNMTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL24452647 | 0.79 | PNMT (0.53) | SRD5A1PNMTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL15086540 | 0.79 | PNMT (0.53) | SRD5A1PNMTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL24500955 | 0.79 | SRD5A1 (0.52) | SRD5A1PNMTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL24501866 | 0.79 | SRD5A1 (0.52) | SRD5A1PNMTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL23850011 | 0.79 | SRD5A1 (0.49) | SRD5A1PNMTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL1863996 | 0.79 | PNMT (0.53) | SRD5A1PNMTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL29495985 | 0.79 | PNMT (0.53) | SRD5A1PNMTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL30686716 | 0.79 | SRD5A1 (0.49) | SRD5A1PNMTCHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |