Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 13/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035444 | 1.00 | GHSR (0.40) | GHSRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21035450 | 1.00 | GHSR (0.40) | GHSRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21035364 | 0.99 | PSEN1 (0.40) | GHSRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21035365 | 0.99 | PSEN1 (0.40) | GHSRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21002020 | 0.99 | PSEN1 (0.40) | GHSRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21002021 | 0.99 | PSEN1 (0.40) | GHSRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21035362 | 0.99 | PSEN1 (0.40) | GHSRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21002063 | 0.99 | PSEN1 (0.40) | GHSRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21002064 | 0.99 | PSEN1 (0.40) | GHSRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21002019 | 0.99 | PSEN1 (0.40) | GHSRPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |