Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 3/20 | 0.62 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2101553 | 0.87 | CENPE (0.68) | CENPEKIFC1S1PR1 | |
| SCHEMBL3462238 | 0.87 | CENPE (0.68) | CENPEKIFC1S1PR1 | |
| SCHEMBL13161850 | 0.87 | CENPE (0.56) | CENPEKIFC1S1PR1 | |
| SCHEMBL3462261 | 0.87 | CENPE (0.56) | CENPEKIFC1S1PR1 | |
| SCHEMBL2105447 | 0.84 | CENPE (0.86) | CENPEKIFC1S1PR1 | |
| SCHEMBL3461806 | 0.84 | CENPE (0.86) | CENPEKIFC1S1PR1 | |
| SCHEMBL2101559 | 0.81 | CENPE (0.69) | CENPEKIFC1S1PR1 | |
| SCHEMBL4428105 | 0.81 | CENPE (0.77) | CENPEKIFC1S1PR1 | |
| SCHEMBL2103186 | 0.81 | CENPE (0.77) | CENPEKIFC1S1PR1 | |
| SCHEMBL3213358 | 0.81 | CENPE (0.77) | CENPEKIFC1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163919-B2 | Imidazopyridinyl benzamide mitotic kinesin inhibitors | CYTOKINETICS, INCORPORATED (US) | 2012-04-24 | — | — | US | disclosed |