Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 9/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 9/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 6/20 | 0.41 |
| ▸ | MMP13 | P45452 | 6/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21034928 | 1.00 | MMP1 (0.42) | MMP1ADAM17KMT2ANPSR1MMP3 | |
| SCHEMBL21035335 | 0.92 | MMP1 (0.47) | MMP1ADAM17KMT2ANPSR1MMP3 | |
| SCHEMBL21035339 | 0.92 | MMP1 (0.47) | MMP1ADAM17KMT2ANPSR1MMP3 | |
| SCHEMBL21035336 | 0.92 | MMP1 (0.47) | MMP1ADAM17KMT2ANPSR1MMP3 | |
| SCHEMBL21035579 | 0.90 | MMP1 (0.42) | MMP1ADAM17KMT2ANPSR1MMP3 | |
| SCHEMBL21034930 | 0.90 | MMP1 (0.42) | MMP1ADAM17KMT2ANPSR1MMP3 | |
| SCHEMBL21035125 | 0.90 | MMP1 (0.46) | MMP1ADAM17KMT2ANPSR1MMP3 | |
| SCHEMBL21035575 | 0.90 | MMP1 (0.46) | MMP1ADAM17KMT2ANPSR1MMP3 | |
| SCHEMBL21035083 | 0.90 | MMP1 (0.46) | MMP1ADAM17KMT2ANPSR1MMP3 | |
| SCHEMBL21035659 | 0.90 | MMP1 (0.46) | MMP1ADAM17KMT2ANPSR1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |