SCHEMBL21036897

SCHEMBL21036897

C=C1C2(C)c3ccc4c(oc5ccccc54)c3N3C=CN(C)C3C12C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23017573 0.80 MEN1 (0.34) MEN1CYP2C19KMT2APGR
SCHEMBL20169280 0.77 MEN1 (0.34) MEN1CYP2C19KMT2APGR
SCHEMBL21415943 0.76 MEN1 (0.31) MEN1CYP2C19KMT2A
SCHEMBL20922373 0.73
SCHEMBL22238220 0.71
SCHEMBL14878701 0.71 MEN1 (0.34) MEN1CYP2C19KMT2APGR
SCHEMBL18456149 0.71 LMNA (0.31)
SCHEMBL24219817 0.70 NPC1 (0.30)
SCHEMBL16558106 0.69 HRH4 (0.36) MEN1CYP2C19KMT2APGR
SCHEMBL21788738 0.69 HRH4 (0.36) MEN1CYP2C19KMT2APGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4212540-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-07-19 EP disclosed
EP-3878855-A1 CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES University of Southern California (US) 2021-09-15 EP disclosed
EP-3816175-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-05-05 EP disclosed
EP-3489243-B1 CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES UNIV SOUTHERN CALIFORNIA (US) 2021-04-21 EP disclosed
EP-3689890-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2020-08-05 EP disclosed
EP-3061759-B1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO (JP) 2019-12-25 EP disclosed
EP-3489243-A1 CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES University of Southern California (US) 2019-05-29 EP disclosed