Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19336852 | 0.79 | HTT (0.49) | ADORA2BAPEX1MAPTSMN1; SMN2HTT | |
| SCHEMBL31098153 | 0.79 | HTT (0.49) | ADORA2BAPEX1MAPTSMN1; SMN2HTT | |
| SCHEMBL8945262 | 0.79 | NPSR1 (0.50) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL17935736 | 0.79 | APEX1 (0.54) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL191729 | 0.77 | NPSR1 (0.58) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL16004445 | 0.77 | NPSR1 (0.52) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL11637084 | 0.75 | MAPT (0.53) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL16004375 | 0.74 | NPSR1 (0.58) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL16004435 | 0.71 | NPSR1 (0.53) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL31098092 | 0.71 | MGLL (0.53) | ADORA2BAPEX1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019102142-A1 | POLYURETHANE-BASED COMPOSITION | BOSTIK SA (FR) | 2019-05-31 | — | — | WO | disclosed |