Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 5/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21037326 | 0.91 | RPS6KA3 (0.36) | APPRPS6KA3ALDH1A1MEN1KMT2A | |
| SCHEMBL21160423 | 0.89 | ALDH1A1 (0.33) | APPRPS6KA3ALDH1A1MEN1KMT2A | |
| SCHEMBL21160458 | 0.89 | ALDH1A1 (0.36) | APPRPS6KA3ALDH1A1MEN1KMT2A | |
| SCHEMBL21234685 | 0.88 | APP (0.43) | APPRPS6KA3ALDH1A1MEN1KMT2A | |
| SCHEMBL21160428 | 0.87 | ALDH1A1 (0.36) | APPRPS6KA3ALDH1A1MEN1KMT2A | |
| SCHEMBL21037880 | 0.86 | MEN1 (0.34) | RPS6KA3ALDH1A1MEN1KMT2A | |
| SCHEMBL21160450 | 0.86 | RPS6KA3 (0.34) | APPRPS6KA3ALDH1A1MEN1KMT2A | |
| SCHEMBL21234697 | 0.86 | RPS6KA3 (0.34) | APPRPS6KA3ALDH1A1MEN1KMT2A | |
| SCHEMBL22313935 | 0.86 | APP (0.41) | APPMAPT | |
| SCHEMBL21037324 | 0.85 | ALDH1A1 (0.33) | RPS6KA3ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-06-20 | — | — | US | disclosed |
| EP-3489324-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | East China University of Science and Technology (CN) | 2019-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | HNRNPF, HNRNPUL2, RAB5IF | APP 2001/4885RPS6KA3 2845/4885ALDH1A1 3152/4885 |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | HNRNPF, HNRNPUL2, RAB5IF | APP 2001/4885RPS6KA3 2845/4885ALDH1A1 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.