SCHEMBL21037327

SCHEMBL21037327

CN(CCO)c1ccc(-c2ccc(C=O)s2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.52
CYP2E1 P05181 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2A6 P11509 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2B6 P20813 1/20 0.40
CYP2C19 P33261 1/20 0.40
PGR P06401 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 2/20 0.37
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
PRF1 P14222 2/20 0.36
DPP4 P27487 1/20 0.36
CYBB P04839 1/20 0.35
NOX4 Q9NPH5 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11937048 0.80 APP (0.62) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL21036842 0.79 DPP4 (0.41) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL21160410 0.78 MAPT (0.64) APPMAPT
SCHEMBL34475129 0.77 APP (0.58) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL13626608 0.76 MAPT (0.39) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL3630228 0.76 APP (0.81) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL1957123 0.75 ALDH1A1 (0.38) L3MBTL1DPP4
SCHEMBL16334781 0.75 APP (0.73) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL24992338 0.74 CYP2A6 (0.35) APPCYP2A6HSD17B1HSD17B2
SCHEMBL15859227 0.74 APP (0.56) APPCYP2E1CYP3A4CYP2A6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119874693-A Abeta plaque dual-mode imaging probe and preparation method and application thereof 华东理工大学 2025-04-25 CN claimed
CN-119874693-A Abeta plaque dual-mode imaging probe and preparation method and application thereof 华东理工大学 2025-04-25 CN disclosed
WO-2023011658-A1 METHOD FOR DETECTING AND QUANTIFYING RNA 纳莹(上海)生物科技有限公司 2023-02-09 WO disclosed
WO-2023011657-A1 METHOD FOR DETECTING AND QUANTIFYING RNA 纳莹(上海)生物科技有限公司 2023-02-09 WO disclosed
US-11209437-B2 Fluorescent probe and preparation method and use thereof FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY (CN) 2021-12-28 US disclosed
US-20190187144-A1 FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2019-06-20 US disclosed
EP-3489324-A1 FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF East China University of Science and Technology (CN) 2019-05-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190187144-A1 FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF HNRNPF, HNRNPUL2, RAB5IF APP 2001/4885CYP2E1 4168/4885CYP3A4 3630/4885
US-11209437-B2 Fluorescent probe and preparation method and use thereof HNRNPF, HNRNPUL2, RAB5IF APP 2001/4885CYP2E1 4168/4885CYP3A4 3630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.