Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044848 | 0.89 | EPHX2 (0.58) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL14218702 | 0.87 | EPHX2 (0.67) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL15332367 | 0.81 | EPHX2 (0.60) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL24359573 | 0.81 | EPHX2 (0.56) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL14067244 | 0.80 | EPHX2 (0.67) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL29579887 | 0.79 | EPHX2 (0.57) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL2629391 | 0.78 | EPHX2 (0.54) | EPHX2KMT2AALDH1A1CASP3CASP2 | |
| SCHEMBL29778121 | 0.77 | EPHX2 (1.00) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL4705905 | 0.77 | EPHX2 (0.68) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL24200101 | 0.77 | EPHX2 (1.00) | EPHX2KMT2AALDH1A1KDM4EHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111430575-A | Organic electroluminescent device and display device including the same | 三星显示有限公司 | 2020-07-17 | — | — | CN | disclosed |
| WO-2019102240-A1 | METHOD FOR THE MANUFACTURE OF LUMATEPERONE AND ITS SALTS | EGIS GYÓGYSZERGYÁR ZRT. (HU) | 2019-05-31 | — | — | WO | disclosed |