Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21037372 | 0.89 | EPHX2 (0.63) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL11500497 | 0.86 | EPHX2 (0.46) | EPHX2KMT2AALDH1A1KDM4EPPARG | |
| SCHEMBL24359573 | 0.83 | EPHX2 (0.56) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL14218702 | 0.83 | EPHX2 (0.67) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL8267277 | 0.81 | EPHX2 (0.53) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL11839637 | 0.78 | MAPT (0.48) | KMT2AALDH1A1HDAC2HDAC8HDAC6 | |
| SCHEMBL15332367 | 0.78 | EPHX2 (0.60) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL14067244 | 0.76 | EPHX2 (0.67) | EPHX2KMT2AALDH1A1KDM4EHDAC2 | |
| SCHEMBL6540849 | 0.76 | KMT2A (0.50) | EPHX2KMT2AMAPTMEN1 | |
| SCHEMBL461664 | 0.76 | CRBN (0.45) | KMT2AALDH1A1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235054-A1 | Novel encoding method for \"one-bead one-compound\" combinatorial libraries | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-11-25 | — | — | US | disclosed |
| WO-2004087933-A2 | A NOVEL ENCODING METHOD FOR 'ONE-BEAD ONE-COMPOUND' COMBINATORIAL LIBRARIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-10-14 | — | — | WO | disclosed |