Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 17/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | CASP1 | P29466 | 4/20 | 0.42 |
| ▸ | CASP7 | P55210 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCND2 | P30279 | 1/20 | 0.40 |
| ▸ | CCND3 | P30281 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544265 | 0.87 | CYP1A2 (0.60) | CYP1A2ALDH1A1CYP3A4CYP2C19CLK4 | |
| SCHEMBL18544270 | 0.83 | PDE10A (0.39) | CYP1A2ALDH1A1CYP3A4CYP2C19CLK4 | |
| SCHEMBL21428786 | 0.81 | CYP1A2 (0.40) | CYP1A2ALDH1A1CYP3A4CYP2C19CLK4 | |
| SCHEMBL20687533 | 0.80 | PDE10A (0.37) | CYP1A2ALDH1A1CYP3A4CYP2C19CLK4 | |
| SCHEMBL21321491 | 0.80 | CYP1A2 (0.40) | CYP1A2ALDH1A1CYP3A4CYP2C19CLK4 | |
| SCHEMBL25024255 | 0.80 | CYP1A2 (0.44) | CYP1A2ALDH1A1CYP3A4CYP2C19CLK4 | |
| SCHEMBL21428647 | 0.79 | KCNH2 (0.46) | CYP1A2ALDH1A1CYP3A4CYP2C19CLK4 | |
| SCHEMBL15850811 | 0.78 | CYP1A2 (0.41) | CYP1A2ALDH1A1CYP3A4CYP2C19CLK4 | |
| SCHEMBL3842971 | 0.77 | CYP1A2 (0.38) | CYP1A2ALDH1A1CYP3A4CYP2C19CLK4 | |
| SCHEMBL21409390 | 0.77 | CYP1A2 (0.39) | CYP1A2ALDH1A1CYP3A4CYP2C19CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640488-B2 | Antibacterial compounds | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2020-05-05 | — | — | US | disclosed |
| US-10633366-B2 | Antibacterial compounds | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2020-04-28 | — | — | US | disclosed |
| US-20200095225-A9 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2020-03-26 | — | — | US | disclosed |
| US-20190256495-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2019-08-22 | — | — | US | disclosed |
| US-20190161472-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190161472-A1 | NEW ANTIBACTERIAL COMPOUNDS | MRPL21, LAS1L, MRPL19 | CYP1A2 1035/4885ALDH1A1 830/4885CYP3A4 2112/4885 |
| US-20200095225-A9 | NEW ANTIBACTERIAL COMPOUNDS | MRPL21, CLPP, NRDC | CYP1A2 4147/4885ALDH1A1 4199/4885CYP3A4 3159/4885 |
| US-10633366-B2 | Antibacterial compounds | MRPL21, LAS1L, MRPL19 | CYP1A2 584/4885ALDH1A1 784/4885CYP3A4 1529/4885 |
| US-20190256495-A1 | NEW ANTIBACTERIAL COMPOUNDS | MRPL21, CLPP, NRDC | CYP1A2 4147/4885ALDH1A1 4199/4885CYP3A4 3159/4885 |
| US-10640488-B2 | Antibacterial compounds | MRPL21, CLPP, NRDC | CYP1A2 3385/4885ALDH1A1 3914/4885CYP3A4 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.