SCHEMBL2104137

SCHEMBL2104137

C=C[Si](CCCC)(NC)NC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2101223 0.85
SCHEMBL2101663 0.79 TSHR (0.33) TSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL2271060 0.76 TSHR (0.35) TSHRALDH1A1ZDHHC20ZDHHC2FAAH
SCHEMBL2104547 0.74
SCHEMBL2101105 0.73 TSHR (0.32) TSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL10592874 0.71 TSHR (0.31) TSHRALDH1A1
SCHEMBL2275019 0.71 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL29156496 0.71 TSHR (0.43) TSHRALDH1A1ZDHHC20ZDHHC2FAAH
SCHEMBL2272463 0.70 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL1474752 0.69 TSHR (0.41) TSHRALDH1A1ZDHHC20ZDHHC2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed