Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19623991 | 0.93 | THRB (0.37) | THRBMAPTSMN1; SMN2HPGDTSHR | |
| SCHEMBL18904643 | 0.88 | MAPT (0.37) | THRBMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL18904666 | 0.86 | MAPT (0.32) | THRBMAPTKMT2AHPGDMEN1 | |
| SCHEMBL18904645 | 0.85 | MAPT (0.38) | THRBMAPTNPC1LMNACYP3A4 | |
| SCHEMBL17933594 | 0.82 | MAPT (0.42) | THRBMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL18904664 | 0.82 | NPC1 (0.35) | THRBMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL19497860 | 0.82 | THRB (0.45) | THRBMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL20089572 | 0.82 | MAPT (0.36) | THRBMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL19929461 | 0.82 | THRB (0.38) | THRBMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL17933720 | 0.81 | THRB (0.49) | THRBMAPTSMN1; SMN2PRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019102922-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER OF SAME, OPTICALLY ANISOTROPIC BODY, AND DISPLAY ELEMENT | DIC株式会社 | 2019-05-31 | — | — | WO | disclosed |