Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 8/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 6/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16593355 | 0.87 | CHRM1 (0.63) | CHRM1 | |
| SCHEMBL16593193 | 0.87 | CHRM1 (0.63) | CHRM1 | |
| SCHEMBL16593210 | 0.84 | CHRM1 (0.62) | P2RX3CHRM1 | |
| SCHEMBL21042773 | 0.82 | CHRM1 (0.61) | CHRM1 | |
| SCHEMBL16593317 | 0.82 | CHRM1 (0.61) | CHRM1 | |
| SCHEMBL19997556 | 0.78 | RPS6KB1 (0.42) | — | |
| SCHEMBL16593189 | 0.78 | CHRM1 (0.57) | CHRM1 | |
| SCHEMBL16593190 | 0.78 | CHRM1 (0.57) | CHRM1 | |
| SCHEMBL16593192 | 0.78 | CHRM1 (0.57) | CHRM1 | |
| SCHEMBL21042600 | 0.77 | CHRM1 (0.76) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-A1 | 4-AZAINDOLE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |