Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19997557 | 0.87 | CCNC (0.41) | ADRA1DL3MBTL1KDM4E | |
| SCHEMBL16628330 | 0.86 | CHRM1 (0.43) | RPS6KB1POLBGRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL21042584 | 0.85 | POLB (0.42) | RPS6KB1POLBNR3C2SMN1; SMN2ALDH1A1 | |
| SCHEMBL22001379 | 0.79 | LOX (0.42) | ADRA1DGRM2 | |
| SCHEMBL22001748 | 0.79 | ALDH1A1 (0.49) | POLBSMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL16628263 | 0.79 | POLB (0.56) | RPS6KB1POLBGRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL21042591 | 0.78 | P2RX3 (0.49) | — | |
| SCHEMBL19997529 | 0.78 | ADRA1D (0.48) | ADRA1DSMN1; SMN2TP53 | |
| SCHEMBL21042773 | 0.78 | CHRM1 (0.61) | — | |
| SCHEMBL16593317 | 0.78 | CHRM1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926312-B2 | 4-azaindole derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-03-27 | — | — | US | disclosed |