Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.48 |
| ▸ | WNT1 | P04628 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16757952 | 0.92 | GPR119 (0.47) | GPR119WNT1GSK3BDYRK1ACNR2 | |
| SCHEMBL16757949 | 0.92 | GPR119 (0.47) | GPR119WNT1GSK3BDYRK1ACNR2 | |
| SCHEMBL16757807 | 0.91 | GPR119 (0.48) | GPR119WNT1GSK3BDYRK1ACNR2 | |
| SCHEMBL16757803 | 0.91 | GPR119 (0.48) | GPR119WNT1GSK3BDYRK1ACNR2 | |
| SCHEMBL18818387 | 0.90 | GPR119 (0.47) | GPR119WNT1GSK3BDYRK1ACNR2 | |
| SCHEMBL16769052 | 0.87 | GPR119 (0.51) | GPR119WNT1GSK3BDYRK1ACYP4F2 | |
| SCHEMBL18848890 | 0.87 | GPR119 (0.49) | GPR119WNT1GSK3BDYRK1ACNR2 | |
| SCHEMBL16757794 | 0.87 | GPR119 (0.45) | GPR119WNT1GSK3BDYRK1ACYP4F2 | |
| SCHEMBL16758028 | 0.87 | GPR119 (0.45) | GPR119WNT1GSK3BDYRK1ACYP4F2 | |
| SCHEMBL16758097 | 0.87 | GPR119 (0.53) | GPR119WNT1GSK3BDYRK1ACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074384-B1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-05-22 | — | — | EP | disclosed |