Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18848900 | 0.88 | PDK2 (0.41) | GPR119CYP4F2CYP4A11PDK2 | |
| SCHEMBL16758018 | 0.87 | PDK2 (0.42) | GPR119CYP4F2CYP4A11PDK2 | |
| SCHEMBL16758023 | 0.87 | PDK2 (0.42) | GPR119CYP4F2CYP4A11PDK2 | |
| SCHEMBL18849010 | 0.84 | GPR119 (0.43) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL15539479 | 0.83 | POLB (0.46) | GPR119ALOX5APFEN1POLBCYP4F2 | |
| SCHEMBL15539188 | 0.83 | POLB (0.46) | GPR119ALOX5APFEN1POLBCYP4F2 | |
| SCHEMBL15539187 | 0.83 | POLB (0.46) | GPR119ALOX5APFEN1POLBCYP4F2 | |
| SCHEMBL16757844 | 0.82 | CYP4F2 (0.41) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL16758060 | 0.81 | CNR2 (0.39) | GPR119CYP4F2CYP4A11PDK2 | |
| SCHEMBL16758055 | 0.81 | CNR2 (0.39) | GPR119CYP4F2CYP4A11PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074384-B1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-05-22 | — | — | EP | disclosed |