SCHEMBL2104333

SCHEMBL2104333

CCC(C)c1ccccc1[SiH2]NCN(CC)CC

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
CACNA2D1 P54289 1/20 0.32
ATM Q13315 1/20 0.32
NISCH Q9Y2I1 1/20 0.32
KDM4E B2RXH2 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268693 0.82 TSHR (0.48) TSHRATMNISCHKDM4EHTT
SCHEMBL2272263 0.77 TSHR (0.50) TSHRATMNISCHKDM4EHTT
SCHEMBL2101843 0.77 TSHR (0.43) TSHRKDM4EHTT
SCHEMBL2271141 0.74 TSHR (0.50) TSHRATMNISCHKDM4EHTT
SCHEMBL2103512 0.72 CACNA2D1 (0.33) TSHRCACNA2D1KDM4E
SCHEMBL2277062 0.72 TSHR (0.52) TSHRATMNISCHKDM4EHTT
SCHEMBL2269777 0.70 TSHR (0.53) TSHRATMNISCHKDM4EHTT
SCHEMBL2101823 0.70 KCNH2 (0.37) CACNA2D1KDM4E
SCHEMBL994607 0.68 TSHR (0.73) TSHRATMNISCHKDM4EHTT
SCHEMBL29066958 0.67 TSHR (0.50) TSHRATMNISCHKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed