SCHEMBL21043404

SCHEMBL21043404

C=CC(=O)OCC(COc1ccc(OC)cc1)OC(=O)C=C

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
CYP2C9 P11712 1/20 0.48
THRB P10828 1/20 0.42
AR P10275 1/20 0.41
ALDH1A1 P00352 2/20 0.40
TGM2 P21980 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KMT2A Q03164 1/20 0.39
FFAR1 O14842 1/20 0.39
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
CYP19A1 P11511 1/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PKM P14618 1/20 0.38
MAOB P27338 1/20 0.37
DRD3 P35462 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19944466 0.94 CYP2C9 (0.53) TSHRCYP2C9THRBALDH1A1TGM2
SCHEMBL17933431 0.91 KMT2A (0.46) TSHRCYP2C9ALDH1A1KMT2AKDM4E
SCHEMBL19787887 0.89 TSHR (0.42) TSHRCYP2C9THRBARKMT2A
SCHEMBL14173294 0.89 THRB (0.44) TSHRCYP2C9THRBARALDH1A1
SCHEMBL13869325 0.89 THRB (0.44) TSHRCYP2C9THRBARALDH1A1
SCHEMBL14173315 0.89 THRB (0.44) TSHRCYP2C9THRBARALDH1A1
SCHEMBL17933726 0.87 THRB (0.43) TSHRTHRBARGAAMAOB
SCHEMBL14173314 0.86 THRB (0.42) TSHRCYP2C9THRBARALDH1A1
SCHEMBL13865637 0.86 ACACB (0.44) TSHRTHRBARFFAR1
SCHEMBL14173295 0.86 THRB (0.42) TSHRCYP2C9THRBARALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019102922-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER OF SAME, OPTICALLY ANISOTROPIC BODY, AND DISPLAY ELEMENT DIC株式会社 2019-05-31 WO disclosed