Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16593247 | 1.00 | CHRM1 (0.59) | CHRM1 | |
| SCHEMBL21043065 | 0.89 | CHRM1 (0.62) | CHRM1 | |
| SCHEMBL16593259 | 0.89 | CHRM1 (0.62) | CHRM1 | |
| SCHEMBL21043048 | 0.88 | CHRM1 (0.62) | CHRM1 | |
| SCHEMBL16593241 | 0.88 | CHRM1 (0.62) | CHRM1 | |
| SCHEMBL16593268 | 0.86 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL21042582 | 0.86 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL22001185 | 0.84 | PDE10A (0.48) | CHRM1 | |
| SCHEMBL16593302 | 0.83 | CHRM1 (0.70) | CHRM1 | |
| SCHEMBL22001387 | 0.83 | CHRM1 (0.70) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-A1 | 4-AZAINDOLE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |