Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043873 | 0.93 | HDAC1 (0.42) | HDAC1HDAC8HDAC6ATAD2P2RX7 | |
| SCHEMBL21043852 | 0.90 | ATAD2 (0.45) | HDAC1HDAC8HDAC6ATAD2CYP1A2 | |
| SCHEMBL21043810 | 0.87 | ATAD2 (0.46) | HDAC1HDAC8HDAC6ATAD2CYP1A2 | |
| SCHEMBL21043773 | 0.87 | ATAD2 (0.49) | HDAC1HDAC8HDAC6ATAD2CYP1A2 | |
| SCHEMBL21043798 | 0.86 | ATAD2 (0.43) | HDAC1HDAC8HDAC6ATAD2P2RX7 | |
| SCHEMBL21043839 | 0.84 | ATAD2 (0.45) | HDAC1HDAC8HDAC6ATAD2CYP1A2 | |
| SCHEMBL21043837 | 0.84 | ATAD2 (0.46) | HDAC1HDAC8HDAC6ATAD2CYP1A2 | |
| SCHEMBL21043874 | 0.83 | ATAD2 (0.44) | HDAC1HDAC8HDAC6ATAD2P2RX7 | |
| SCHEMBL21043861 | 0.83 | ATAD2 (0.46) | HDAC1HDAC8HDAC6ATAD2CYP1A2 | |
| SCHEMBL21043866 | 0.83 | ATAD2 (0.46) | HDAC1HDAC8HDAC6ATAD2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |