SCHEMBL21044851

SCHEMBL21044851

COc1cc(OC)c(NC(=O)C2=Cc3ccccc3/C(=N\Nc3cc(C(=O)Nc4ccc(C(N)=O)cc4)ccc3OC)C2=O)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDE4D Q08499 2/20 0.42
▸ MAPT P10636 6/20 0.41
▸ POLB P06746 1/20 0.41
▸ KDM4E B2RXH2 6/20 0.41
▸ KMT2A Q03164 7/20 0.41
▸ MEN1 O00255 5/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ PDE4A P27815 1/20 0.40
▸ PDE4B Q07343 1/20 0.40
▸ PDE4C Q08493 1/20 0.40
▸ HDAC1 Q13547 1/20 0.39
▸ HDAC8 Q9BY41 1/20 0.39
▸ HDAC6 Q9UBN7 1/20 0.39
▸ TP53 P04637 2/20 0.39
▸ MAPK14 Q16539 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.38
▸ THRB P10828 1/20 0.38
▸ HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17491828 0.91 KMT2A (0.47) PDE4DMAPTKDM4EKMT2AMEN1
SCHEMBL12393169 0.86 KMT2A (0.47) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL21044834 0.86 KMT2A (0.48) PDE4DMAPTPOLBKMT2AMEN1
SCHEMBL29351700 0.86 KMT2A (0.48) PDE4DMAPTPOLBKMT2AMEN1
SCHEMBL21436648 0.85 MEN1 (0.47) PDE4DMAPTPOLBKMT2AMEN1
SCHEMBL10036416 0.84 MEN1 (0.48) MAPTPOLBKMT2AMEN1ALDH1A1
SCHEMBL21436712 0.84 KMT2A (0.47) PDE4DMAPTPOLBKMT2AMEN1
SCHEMBL23717238 0.84 PDE4D (0.42) PDE4DMAPTPOLBKDM4EKMT2A
SCHEMBL21044859 0.82 CPT1A (0.42) MAPTPOLBKDM4EKMT2AMEN1
SCHEMBL21436589 0.81 MEN1 (0.48) MAPTKDM4EKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577368-B2 Opaque polyester-based materials HOLLAND COLOURS N.V. (NL) 2026-03-17 — — US claimed
US-20220282060-A1 OPAQUE POLYESTER-BASED MATERIALS HOLLAND COLOURS N.V. (NL) 2022-09-08 — — US claimed
EP-3983195-A1 OPAQUE POLYESTER-BASED MATERIALS Holland Colours N. V. (NL) 2022-04-20 — — EP claimed
CN-114127189-A Lightproof polyester-based materials 荷兰颜料股份有限公司 2022-03-01 — — CN claimed
US-12577368-B2 Opaque polyester-based materials HOLLAND COLOURS N.V. (NL) 2026-03-17 — — US disclosed
WO-2025136104-A1 BIO-SOURCED PHTHALOCYANINE COMPLEX, PREPARATION AND USE THEREOF HOLLAND COLOURS N.V. (NL) 2025-06-26 — — WO disclosed
EP-4574911-A1 BIO-SOURCED PHTHALOCYANINE COMPLEX, PREPARATION AND USE THEREOF Holland Colours N. V. (NL) 2025-06-25 — — EP disclosed
US-12319037-B2 Transparent polymer film with discoloration compensation KLÖCKNER PENTAPLAST GMBH (DE) 2025-06-03 — — US disclosed
EP-3660087-B1 METHOD AND MATERIAL FOR THE PRODUCTION OF THREE-DIMENSIONAL OBJECTS BY ENERGY IMPULSE-INDUCED TRANSFER PRINTING IVOCLAR VIVADENT AG (LI) 2024-05-29 — — EP disclosed
US-20240083151-A1 TRANSPARENT POLYMER FILM WITH DISCOLORATION COMPENSATION KLÖCKNER PENTAPLAST GMBH (DE) 2024-03-14 — — US disclosed
US-11858241-B2 Transparent polymer film with discolouration compensation KLÖCKNER PENTAPLAST GMBH (DE) 2024-01-02 — — US disclosed
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMINY GMBH (DE) 2023-10-05 — — US disclosed
US-20200172747-A1 Process And Material For Producing 3D Objects By Energy-Pulse-Induced Transfer Printing IO TECH GROUP LTD. (GB) 2020-06-04 — — US disclosed
EP-3660087-A1 METHOD AND MATERIAL FOR THE PRODUCTION OF THREE-DIMENSIONAL OBJECTS BY ENERGY IMPULSE-INDUCED TRANSFER PRINTING Ivoclar Vivadent AG (LI) 2020-06-03 — — EP disclosed
WO-2020007510-A1 MULTICOMPONENT PUR COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 — — WO disclosed
WO-2020007511-A1 MULTICOMPONENT SILICONE COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 — — WO disclosed
WO-2019228888-A1 TRANSPARENT POLYMER FILM WITH DISCOLORATION COMPENSATION KLÖCKNER PENTAPLAST GMBH (DE) 2019-12-05 — — WO disclosed
WO-2019192916-A1 BICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2019-10-10 — — WO disclosed
US-20190243268-A1 MAGENTA TONER ZEON CORPORATION (JP) 2019-08-08 — — US disclosed
EP-3492986-A1 MAGENTA TONER Zeon Corporation (JP) 2019-06-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577368-B2 Opaque polyester-based materials STRA6, RICTOR, RPL35 PDE4D 4705/4885MAPT 2046/4885POLB 2668/4885
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER KRT18, MKI67, IK PDE4D 1293/4885MAPT 621/4885POLB 1066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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