SCHEMBL21436648

SCHEMBL21436648

COc1ccc(C(=O)Nc2ccccc2)cc1N/N=C1\C(=O)C(C(N)=O)=Cc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.47
▸ KMT2A Q03164 4/20 0.47
▸ MAPT P10636 2/20 0.46
▸ POLB P06746 2/20 0.46
▸ PDE4D Q08499 2/20 0.43
▸ PDE4A P27815 1/20 0.43
▸ PDE4B Q07343 1/20 0.43
▸ PDE4C Q08493 1/20 0.43
▸ ALDH1A1 P00352 2/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ HDAC1 Q13547 2/20 0.42
▸ HDAC8 Q9BY41 2/20 0.42
▸ HDAC6 Q9UBN7 2/20 0.42
▸ CYP1A2 P05177 1/20 0.41
▸ ABCG2 Q9UNQ0 1/20 0.41
▸ LMNA P02545 1/20 0.40
▸ NPC1 O15118 1/20 0.39
▸ TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351700 0.94 KMT2A (0.48) MEN1KMT2AMAPTPOLBPDE4D
SCHEMBL21044834 0.94 KMT2A (0.48) MEN1KMT2AMAPTPOLBPDE4D
SCHEMBL21436712 0.90 KMT2A (0.47) MEN1KMT2AMAPTPOLBPDE4D
SCHEMBL10036416 0.89 MEN1 (0.48) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL12393169 0.87 KMT2A (0.47) MEN1KMT2AMAPTALDH1A1HDAC1
SCHEMBL17491828 0.86 KMT2A (0.47) MEN1KMT2AMAPTPDE4DPDE4A
SCHEMBL21044851 0.85 PDE4D (0.42) MEN1KMT2AMAPTPOLBPDE4D
SCHEMBL21044859 0.84 CPT1A (0.42) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL21044856 0.84 MEN1 (0.54) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL21436589 0.84 MEN1 (0.48) MEN1KMT2AMAPTALDH1A1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMINY GMBH (DE) 2023-10-05 — — US disclosed
EP-4171500-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER Wella Germany GmbH (DE) 2023-05-03 — — EP disclosed
US-11324688-B2 Bicomponent composition WELLA INTERNATIONAL OPERATIONS SWI (CH) 2022-05-10 — — US disclosed
US-20220054392-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2022-02-24 — — US disclosed
US-20220016017-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2022-01-20 — — US disclosed
WO-2022002983-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2022-01-06 — — WO disclosed
EP-3890683-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-10-13 — — EP disclosed
US-20210290519-A1 MULTICOMPONENT SILICONE COMPOSITION WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2021-09-23 — — US disclosed
US-20210290518-A1 MULTICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2021-09-23 — — US disclosed
US-20210145726-A1 BICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2021-05-20 — — US disclosed
EP-3817825-A1 MULTICOMPONENT PUR COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-05-12 — — EP disclosed
EP-3817710-A1 MULTICOMPONENT SILICONE COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-05-12 — — EP disclosed
EP-3787753-A1 MULTICOMPONENT COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-03-10 — — EP disclosed
EP-3773922-A1 BICOMPONENT COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-02-17 — — EP disclosed
WO-2020114647-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-06-11 — — WO disclosed
WO-2020007510-A1 MULTICOMPONENT PUR COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 — — WO disclosed
WO-2020007511-A1 MULTICOMPONENT SILICONE COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 — — WO disclosed
WO-2019192916-A1 BICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2019-10-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220016017-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES KRT18, ITGA5, FLNA MEN1 2431/4885KMT2A 586/4885MAPT 360/4885
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER KRT18, MKI67, IK MEN1 811/4885KMT2A 876/4885MAPT 621/4885
US-20210290519-A1 MULTICOMPONENT SILICONE COMPOSITION CUTA, CD99, PLOD3 MEN1 10/4885KMT2A 648/4885MAPT 2078/4885
US-20220054392-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION KRT18, PRKDC, VIM MEN1 1309/4885KMT2A 1653/4885MAPT 817/4885
US-11324688-B2 Bicomponent composition KRT18, EXOSC10, EXOSC9 MEN1 1869/4885KMT2A 1253/4885MAPT 1247/4885
US-20210290518-A1 MULTICOMPONENT COMPOSITION KRT18, INCENP, IK MEN1 585/4885KMT2A 684/4885MAPT 1146/4885
US-20210145726-A1 BICOMPONENT COMPOSITION KRT18, EXOSC10, EXOSC9 MEN1 1869/4885KMT2A 1253/4885MAPT 1247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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