SCHEMBL21045006

SCHEMBL21045006

C=CC1=C(c2ccccc2)c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.39
TSHR P16473 1/20 0.39
FGFR1 P11362 4/20 0.38
FGFR2 P21802 4/20 0.38
FGFR4 P22455 4/20 0.38
FGFR3 P22607 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
CDC25A P30304 1/20 0.37
CDC25B P30305 1/20 0.37
SRC P12931 2/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
P2RX7 Q99572 1/20 0.35
HSD17B10 Q99714 2/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
CYP2A6 P11509 1/20 0.34
MAPK1 P28482 1/20 0.34
MAPT P10636 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30874973 0.84 MAPT (0.50) ALDH1A1FGFR1FGFR2FGFR4FGFR3
SCHEMBL7152778 0.77 ALDH1A1 (0.45) ALDH1A1TSHRTDP1CDC25BHSD17B10
SCHEMBL19879495 0.72 ALDH1A1 (0.50) ALDH1A1FGFR1FGFR2FGFR4FGFR3
Butadiene SCHEMBL9807163 0.67 ALDH1A1 (0.48) ALDH1A1TSHRTDP1HSD17B10HPGD
SCHEMBL8759097 0.67 ALDH1A1 (0.42) ALDH1A1TSHRTDP1HSD17B10HPGD
SCHEMBL76904 0.67 ALDH1A1 (0.46) ALDH1A1TSHRHSD17B10HPGDBCL2L1
SCHEMBL29418124 0.67 ALDH1A1 (0.46) ALDH1A1TSHRHSD17B10HPGDBCL2L1
Styrene SCHEMBL11560726 0.67 ALDH1A1 (0.70) ALDH1A1TSHRTDP1HSD17B10HPGD
SCHEMBL24726902 0.67 ALDH1A1 (0.36) ALDH1A1TSHRTDP1CDC25ACDC25B
SCHEMBL20944787 0.67 ALDH1A1 (0.36) ALDH1A1TSHRTDP1CDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109867590-B Process for preparing stable and thermally polymerizable vinyl, amino or oligomeric phenoxybenzocyclobutene monomers with improved cure kinetics 罗门哈斯电子材料有限责任公司 2022-06-21 CN disclosed
EP-3708559-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVED CURING KINETICS Rohm and Haas Electronic Materials LLC (US) 2020-09-16 EP disclosed
EP-3492444-B1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVED CURING KINETICS ROHM & HAAS ELECT MAT (US) 2020-07-08 EP disclosed
US-20200087429-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVIED CURING KINETICS ROHM & HAAS ELECT MAT (US) 2020-03-19 US disclosed
CN-109867590-A With improve cure kinetics preparation stablize and can the vinyl of thermal polymerization, amino or oligomeric phenoxy group benzocyclobutene monomer method 罗门哈斯电子材料有限责任公司 2019-06-11 CN disclosed
US-20190169327-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVED CURING KINETICS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-06-06 US disclosed
EP-3492444-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVED CURING KINETICS Rohm and Haas Electronic Materials LLC (US) 2019-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087429-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVIED CURING KINETICS APEH, AADAC, KDM8 ALDH1A1 782/4885TSHR 3527/4885FGFR1 2004/4885
US-20190169327-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVED CURING KINETICS APEH, PAH, KDM8 ALDH1A1 713/4885TSHR 3775/4885FGFR1 1893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.