Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19558538 | 0.83 | NPSR1 (0.52) | ALDH1A1SMN1; SMN2GAANPSR1GLO1 | |
| SCHEMBL15913414 | 0.82 | HCAR2 (0.39) | HCAR2ALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL15913690 | 0.80 | HCAR2 (0.38) | HCAR2ALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL15913497 | 0.79 | HCAR2 (0.35) | HCAR2ALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL15913802 | 0.78 | ALDH1A1 (0.40) | HCAR2ALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL15913443 | 0.78 | HCAR2 (0.37) | HCAR2ALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL15913481 | 0.77 | HCAR2 (0.33) | HCAR2ALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL20262479 | 0.76 | HCAR2 (0.45) | HCAR2ALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL15913411 | 0.76 | HCAR2 (0.35) | HCAR2ALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL15913486 | 0.73 | TSHR (0.36) | HCAR2ALDH1A1SMN1; SMN2GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10316338-B1 | Enzymatic process for the preparation of (1S,2R)-2-(difluoromethyl)-1-(propoxycarbonyl)cyclopropanecarboxylic acid | ABB VIE INC. (US) | 2019-06-11 | — | — | US | disclosed |