Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932429 | 0.80 | QPCT (0.57) | TSHRCYP3A4CYP2D6CYP2C19LMNA | |
| SCHEMBL27303234 | 0.75 | HRH3 (0.50) | QPCTQPCTLHRH3HRH4 | |
| SCHEMBL7598349 | 0.73 | CYP3A4 (0.50) | CYP3A4LMNAQPCTQPCTLHRH3 | |
| SCHEMBL5966684 | 0.72 | HRH3 (0.53) | HRH3HRH4 | |
| SCHEMBL3846866 | 0.71 | CYP3A4 (0.67) | CYP3A4LMNAHRH3HRH4 | |
| SCHEMBL1581156 | 0.71 | CYP3A4 (0.67) | CYP3A4LMNAHRH3HRH4 | |
| SCHEMBL4425225 | 0.71 | CYP3A4 (0.50) | TSHRCYP3A4LMNAQPCTQPCTL | |
| SCHEMBL262239 | 0.71 | CYP3A4 (0.67) | CYP3A4LMNAHRH3HRH4 | |
| SCHEMBL22392203 | 0.70 | HRH3 (0.45) | TSHRCYP3A4CYP2D6CYP2C19QPCT | |
| Hydrochloric Acid SCHEMBL7321531 | 0.70 | CYP3A4 (0.65) | CYP3A4LMNAHRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257587-B1 | POLYMER DERIVED FROM LINEAR POLYETHYLENIMINE FOR GENE TRANSFER | CENTRE NAT RECH SCIENT (FR) | 2019-06-12 | — | — | EP | disclosed |