Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634743 | 0.80 | KMT2A (0.49) | KMT2AALDH1A1POLBTSHRL3MBTL1 | |
| SCHEMBL2737231 | 0.77 | KMT2A (0.47) | KMT2AALDH1A1POLBTSHRL3MBTL1 | |
| SCHEMBL2635272 | 0.77 | KMT2A (0.56) | KMT2AALDH1A1POLBTSHRL3MBTL1 | |
| SCHEMBL16570031 | 0.74 | KMT2A (0.45) | KMT2AALDH1A1POLBTSHRL3MBTL1 | |
| SCHEMBL2634905 | 0.74 | KMT2A (0.45) | KMT2AALDH1A1POLBTSHRL3MBTL1 | |
| SCHEMBL11294913 | 0.72 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL27244976 | 0.71 | POLB (0.54) | KMT2AALDH1A1POLBTSHRMEN1 | |
| Hydrochloric Acid SCHEMBL4329941 | 0.71 | ALDH1A1 (0.45) | KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL5623571 | 0.71 | POLB (0.54) | KMT2AALDH1A1POLBTSHRMEN1 | |
| SCHEMBL25375819 | 0.69 | GAA (0.50) | KMT2AMEN1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143021-B1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | PFIZER (US) | 2019-06-12 | — | — | EP | disclosed |