SCHEMBL21049231

SCHEMBL21049231

O=C(CCCCCCC(=O)Oc1c(F)c(F)c(F)c(F)c1F)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
DGKA P23743 1/20 0.39
VCAM1 P19320 2/20 0.37
TSHR P16473 1/20 0.37
LMNA P02545 4/20 0.36
PAM P19021 2/20 0.35
ALDH1A1 P00352 1/20 0.35
KDM4E B2RXH2 1/20 0.35
DUSP3 P51452 1/20 0.35
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522462 1.00 KMT2A (0.43) KMT2AMEN1DGKAVCAM1TSHR
SCHEMBL25495837 1.00 KMT2A (0.43) KMT2AMEN1DGKAVCAM1TSHR
SCHEMBL4953772 0.98 KMT2A (0.44) KMT2AMEN1DGKAVCAM1TSHR
SCHEMBL17337909 0.93 KMT2A (0.48) KMT2AMEN1DGKAVCAM1TSHR
SCHEMBL15235923 0.92 DGKA (0.52) KMT2AMEN1DGKATSHRLMNA
SCHEMBL22463686 0.92 DGKA (0.52) KMT2AMEN1DGKATSHRLMNA
SCHEMBL8996129 0.92 KMT2A (0.39) KMT2AMEN1DGKAVCAM1TSHR
SCHEMBL3940182 0.92 KMT2A (0.39) KMT2AMEN1DGKAVCAM1TSHR
SCHEMBL23813738 0.92 PAOX (0.42) KMT2AMEN1DGKAVCAM1TSHR
SCHEMBL22271695 0.92 DGKA (0.52) KMT2AMEN1DGKATSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651910-A1 DUAL LABELLED COMPOUNDS TARGETING THE PROSTATE SPECIFIC MEMBRANE ANTIGEN Centre Hospitalier Universitaire Vaudois (CHUV) (CH) 2025-11-26 EP disclosed
WO-2024153719-A1 DUAL LABELLED COMPOUNDS TARGETING THE PROSTATE SPECIFIC MEMBRANE ANTIGEN CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV) (CH) 2024-07-25 WO disclosed
EP-3494999-A1 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY Technische Universität München (DE) 2019-06-12 EP disclosed