Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278231 | 0.86 | CRBN (0.41) | CRBNDDB1TSHRNPSR1IDO1 | |
| SCHEMBL278097 | 0.86 | — | — | |
| SCHEMBL3825820 | 0.84 | CRBN (0.40) | CRBNDDB1TSHRNPSR1 | |
| SCHEMBL3958832 | 0.84 | CRBN (0.40) | CRBNDDB1TSHRNPSR1 | |
| SCHEMBL17077711 | 0.76 | CRBN (0.38) | CRBNDDB1TSHRNPSR1IDO1 | |
| SCHEMBL785575 | 0.73 | CRBN (0.55) | CRBNDDB1TSHRNPSR1IDO1 | |
| Hydrochloric Acid SCHEMBL5258578 | 0.71 | CRBN (0.53) | CRBNDDB1TSHRNPSR1 | |
| SCHEMBL2702162 | 0.71 | CRBN (0.38) | CRBNDDB1TSHRNPSR1IDO1 | |
| SCHEMBL529832 | 0.71 | CRBN (0.43) | CRBNTSHRNPSR1 | |
| SCHEMBL15898067 | 0.70 | CRBN (0.39) | CRBNDDB1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494109-A1 | METHOD FOR PRODUCING SPIROKETAL-SUBSTITUTED CYCLIC KETOENOLS | Bayer CropScience Aktiengesellschaft (DE) | 2019-06-12 | — | — | EP | disclosed |