⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL753358 | 0.88 | — | — | |
| SCHEMBL383731 | 0.87 | TSHR (0.32) | — | |
| SCHEMBL4818972 | 0.85 | TSHR (0.31) | — | |
| SCHEMBL2621446 | 0.84 | TSHR (0.30) | — | |
| SCHEMBL16504168 | 0.84 | TSHR (0.30) | — | |
| SCHEMBL14136628 | 0.84 | TSHR (0.30) | — | |
| SCHEMBL13033839 | 0.83 | — | — | |
| SCHEMBL22201509 | 0.81 | — | — | |
| SCHEMBL23139033 | 0.81 | — | — | |
| SCHEMBL21395330 | 0.81 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900681-B1 | PHARMACEUTICAL COMPOSITION COMPRISING LIPOPHILIC NUCLEOSIDES | IONOVATION GMBH (DE) | 2019-07-10 | — | — | EP | disclosed |
| US-20190175633-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | IONOVATION GMBH (DE) | 2019-06-13 | — | — | US | disclosed |