SCHEMBL383731

SCHEMBL383731

CC(C)N(C(C)C)P(OCCC#N)OCCC#N

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
NLRP3 Q96P20 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4818972 0.98 TSHR (0.31) TSHRNLRP3
SCHEMBL566248 0.93 TSHR (0.31) TSHR
SCHEMBL10030503 0.93 TSHR (0.35) TSHR
SCHEMBL14136628 0.92 TSHR (0.30) TSHRNLRP3
SCHEMBL2621446 0.92 TSHR (0.30) TSHRNLRP3
SCHEMBL16504168 0.92 TSHR (0.30) TSHRNLRP3
SCHEMBL18541723 0.91
SCHEMBL22743730 0.91 NLRP3 (0.31) NLRP3
SCHEMBL2397817 0.91
SCHEMBL17133199 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 818 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119490394-A Isobutene hydroformylation catalytic system and method for catalytic synthesis of isovaleraldehyde 宁夏天新药业有限公司 2025-02-21 CN claimed
CN-119080856-A Mutant tRNA for codon extension 中外制药株式会社 2024-12-06 CN claimed
CN-118178675-A Supermolecule DNA-PEG-Ferrocene nano gel, preparation method and anti-tumor application 武汉科技大学 2024-06-14 CN claimed
EP-4367244-A1 OLIGONUCLEOTIDE-BASED DELIVERY VEHICLE FOR OLIGONUCLEOTIDES AGENTS AND METHODS OF USE THEREOF Ractigen Therapeutics (CN) 2024-05-15 EP claimed
CN-117916374-A Oligonucleotide-based delivery vehicles for oligonucleotide agents and methods of use thereof 中美瑞康核酸技术(南通)研究院有限公司 2024-04-19 CN claimed
EP-4341270-A1 CHEMICAL PHOSPHORYLATION REAGENTS, PREPARATION, AND THEIR USES Olix US, Inc. (US) 2024-03-27 EP claimed
CN-117580848-A Chemical phosphorylating reagent, preparation and use thereof 奥利克斯美国公司 2024-02-20 CN claimed
CN-114941018-B Synthesis method of cap1 cap analogue 翌圣生物科技(上海)股份有限公司 2023-09-22 CN claimed
WO-2023280190-A1 OLIGONUCLEOTIDE-BASED DELIVERY VEHICLE FOR OLIGONUCLEOTIDES AGENTS AND METHODS OF USE THEREOF RACTIGEN THERAPEUTICS (CN) 2023-01-12 WO claimed
US-20230000983-A1 METHODS AND COMPOSITIONS FOR SYNTHESIS OF TWO-PHOTON CLEAVABLE PHOSPHORAMIDITE MOLECULES FOR OLIGONUCLEOTIDE CONJUGATION CITY UNIVERSITY OF HONG KONG (HK) 2023-01-05 US claimed
EP-3095790-A1 NUCLEOSIDE-LIPID COMPOUNDS WITH PH-SENSITIVE DIALKYLORTHOESTER CHAINS AND THEIR USE FOR TRANSPORTATION OR VECTORIZATION OF AT LEAST ONE THERAPEUTIC AGENT UNIVERSITE DE BORDEAUX (FR) 2016-11-23 EP claimed
EP-2767541-A1 LPA receptor agonists and antagonists Rxbio, Inc. (US) 2014-08-20 EP claimed
US-8461124-B2 Five- and six-membered conformationally locked 2′,4′-carbocyclic ribo-thymidines for the treatment of infections and cancer CHATTOPADHYAYA JYOTI (SE) 2013-06-11 US claimed
JP-4237257-B2 2009-03-11 JP claimed
EP-1021388-B1 PHOSPHORYLATION PROCESS AND CATALYST BIONERIS AB (SE) 2003-06-25 EP claimed
US-6479656-B1 Phosphorylation process and catalyst PERSTORP AB (SE) 2002-11-12 US claimed
JP-2001501910-A 2001-02-13 JP claimed
EP-1021388-A1 PHOSPHORYLATION PROCESS AND CATALYST PERSTORP AB (SE) 2000-07-26 EP claimed
WO-1997034853-A1 PHOSPHORYLATION PROCESS AND CATALYST PERSTORP AB (SE) 1997-09-25 WO claimed
US-5430169-A Method for preparation of sphingoid bases THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1995-07-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000983-A1 METHODS AND COMPOSITIONS FOR SYNTHESIS OF TWO-PHOTON CLEAVABLE PHOSPHORAMIDITE MOLECULES FOR OLIGONUCLEOTIDE CONJUGATION PCNA, POLB, NCL TSHR 3117/4885NLRP3 3872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.