Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17878211 | 0.83 | POLB (0.48) | PARP10MAPTPOLBENPP2CA2 | |
| SCHEMBL7822013 | 0.81 | SRD5A2 (0.61) | PARP10ALDH1A1SMN1; SMN2POLBENPP2 | |
| SCHEMBL10704760 | 0.80 | SRD5A2 (0.50) | PARP10ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL9181081 | 0.79 | CA12 (0.49) | PBRM1ALDH1A1MEN1GAAMAPT | |
| SCHEMBL169521 | 0.78 | CA12 (0.51) | ATMALDH1A1MAPTENPP2CA2 | |
| SCHEMBL26111588 | 0.77 | ALDH1A1 (0.61) | PARP10ATMPBRM1ALDH1A1MITF | |
| SCHEMBL8734462 | 0.77 | PBRM1 (0.70) | PARP10ATMPBRM1ALDH1A1MITF | |
| SCHEMBL203590 | 0.77 | PARP10 (0.59) | PARP10ATMPBRM1ALDH1A1MITF | |
| SCHEMBL27188052 | 0.77 | PARP10 (0.59) | PARP10ATMPBRM1ALDH1A1MITF | |
| SCHEMBL432542 | 0.76 | TDP1 (0.52) | ATMPBRM1ALDH1A1MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190181348-A1 | BRANCH POINT EFFECT ON STRUCTURE AND ELECTRONIC PROPERTIES OF CONJUGATED POLYMERS | UNIV CALIFORNIA (US) | 2019-06-13 | — | — | US | disclosed |