Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | BAD | Q92934 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | NQO1 | P15559 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24133294 | 0.96 | BCL2L1 (0.42) | BCL2L1BADCES1NQO1L3MBTL1 | |
| SCHEMBL1249690 | 0.77 | CES1 (0.42) | BCL2L1BADCES1L3MBTL1HTR2A | |
| SCHEMBL3797823 | 0.77 | BCL2L1 (0.56) | BCL2L1BADNQO1CTRCGRIA1 | |
| SCHEMBL1046490 | 0.77 | BCL2L1 (0.50) | BCL2L1BADCES1NQO1CTRC | |
| SCHEMBL4756408 | 0.76 | CES1 (0.41) | BCL2L1BADCES1L3MBTL1HTR2A | |
| SCHEMBL1660189 | 0.76 | BCL2L1 (0.48) | BCL2L1BADCES1NQO1CTRC | |
| SCHEMBL5768853 | 0.74 | BCL2L1 (0.47) | BCL2L1BADCES1NQO1CTRC | |
| SCHEMBL15054072 | 0.74 | BCL2L1 (0.52) | BCL2L1BADCES1NQO1L3MBTL1 | |
| SCHEMBL14354818 | 0.74 | BCL2L1 (0.47) | BCL2L1BADCES1NQO1L3MBTL1 | |
| SCHEMBL1535927 | 0.73 | BCL2L1 (0.50) | BCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239761-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20240239761-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2024-07-18 | — | — | US | disclosed |
| EP-4310077-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | Medshine Discovery Inc. (CN) | 2024-01-24 | — | — | EP | disclosed |
| US-11576981-B2 | Acyl hydrazone linkers, methods and uses thereof | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2023-02-14 | — | — | US | disclosed |
| US-20200397916-A1 | ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2020-12-24 | — | — | US | disclosed |
| EP-3720842-A1 | ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF | Ontario Institute For Cancer Research (CA) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019109188-A1 | ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2019-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239761-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | CYP3A43, CYP11B2, UGT2B7 | BCL2L1 3207/4885BAD 579/4885CES1 1342/4885 |
| US-20200397916-A1 | ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF | KAT7, AADAC, HDAC7 | BCL2L1 4528/4885BAD 3923/4885CES1 998/4885 |
| US-11576981-B2 | Acyl hydrazone linkers, methods and uses thereof | AADAC, HDAC8, KAT8 | BCL2L1 4245/4885BAD 3685/4885CES1 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.