SCHEMBL2105359

SCHEMBL2105359

CCc1[c]c(I)cc(C(F)(C(F)(F)F)C(F)(F)F)c1-c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.36
AKR1C2 P52895 2/20 0.36
ALDH1A1 P00352 1/20 0.34
AR P10275 2/20 0.33
NPBWR1 P48145 1/20 0.32
MAPT P10636 3/20 0.31
HSD11B1 P28845 1/20 0.31
GHSR Q92847 2/20 0.31
GFER P55789 1/20 0.31
RORC P51449 1/20 0.31
ABCC8 Q09428 1/20 0.30
KCNJ11 Q14654 1/20 0.30
PSD A5PKW4 2/20 0.30
GYS1 P13807 1/20 0.30
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17554823 0.87 AKR1C3 (0.36) AKR1C3AKR1C2ALDH1A1ARNPBWR1
SCHEMBL17554960 0.82 AKR1C3 (0.35) AKR1C3AKR1C2ALDH1A1ARNPBWR1
SCHEMBL2107205 0.77 AKR1C3 (0.37) AKR1C3AKR1C2ALDH1A1ARNPBWR1
SCHEMBL17554936 0.77 AKR1C3 (0.36) AKR1C3AKR1C2ALDH1A1ARNPBWR1
SCHEMBL17554923 0.75 F2RL3 (0.36) AKR1C3AKR1C2ALDH1A1ARMAPT
SCHEMBL1948387 0.74 ALDH1A1 (0.38) AKR1C3AKR1C2ALDH1A1ARMAPT
SCHEMBL2103328 0.74 AKR1C3 (0.38) AKR1C3AKR1C2ALDH1A1ARNPBWR1
SCHEMBL2105515 0.73 AKR1C3 (0.37) AKR1C3AKR1C2ALDH1A1ARNPBWR1
SCHEMBL17554900 0.72 ALDH1A1 (0.36) AKR1C3AKR1C2ALDH1A1ARMAPT
SCHEMBL16462365 0.72 AKR1C3 (0.35) AKR1C3AKR1C2ALDH1A1MAPTHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163804-B2 Composition for preventing harmful organisms MITSUI CHEMICALS, INC. (JP) 2012-04-24 US disclosed