Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14034101 | 0.89 | ALDH1A1 (0.74) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL21054518 | 0.83 | PIK3CA (0.53) | PIKFYVEGSK3BCDK2PIK3CAPIK3CB | |
| SCHEMBL21053855 | 0.83 | PIKFYVE (0.62) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL1862072 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL1858593 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL4439748 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL4438348 | 0.80 | SMN1; SMN2 (0.52) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL4433844 | 0.80 | PIK3CA (0.70) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL4446531 | 0.79 | SMN1; SMN2 (0.51) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL21054789 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1HPGDLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11603372-B2 | Compounds and therapeutic uses thereof | VIOGEN BIOSCIENCES, LLC (US) | 2023-03-14 | — | — | US | disclosed |
| US-20210122752-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VIOGEN BIOSCIENCES, LLC | 2021-04-29 | — | — | US | disclosed |
| US-20210122752-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VIOGEN BIOSCIENCES, LLC | 2021-04-29 | — | — | US | disclosed |
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11603372-B2 | Compounds and therapeutic uses thereof | IL15, IL17A, IL2 | KDM4E 3881/4885ALDH1A1 1513/4885HPGD 3886/4885 |
| US-20210122752-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | IL15, IL17A, IL2 | KDM4E 3881/4885ALDH1A1 1513/4885HPGD 3886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.