Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.68 |
| ▸ | CXCR4 | P61073 | 13/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575215 | 0.97 | HDAC1 (0.65) | HDAC1HDAC6CXCR4CYP2D6CYP3A4 | |
| SCHEMBL13909820 | 0.93 | HDAC1 (0.76) | HDAC1HDAC6CXCR4CYP2D6CYP3A4 | |
| SCHEMBL4065807 | 0.90 | HDAC1 (0.68) | HDAC1HDAC6CXCR4CYP2D6CYP3A4 | |
| SCHEMBL4562865 | 0.88 | HDAC1 (0.69) | HDAC1HDAC6CXCR4CYP2D6CYP3A4 | |
| SCHEMBL4887341 | 0.88 | HDAC1 (0.69) | HDAC1HDAC6CXCR4CYP2D6CYP3A4 | |
| SCHEMBL4065804 | 0.84 | HDAC1 (0.78) | HDAC1HDAC6CXCR4CYP2D6CYP3A4 | |
| SCHEMBL4070374 | 0.84 | HDAC1 (0.64) | HDAC1HDAC6CXCR4CYP2D6CYP3A4 | |
| SCHEMBL14037709 | 0.84 | HDAC1 (0.64) | HDAC1HDAC6CXCR4CYP2D6CYP3A4 | |
| SCHEMBL31380423 | 0.84 | HDAC1 (0.64) | HDAC1HDAC6CXCR4CYP2D6CYP3A4 | |
| SCHEMBL4066161 | 0.83 | HDAC1 (0.63) | HDAC1HDAC6CXCR4CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720494-A2 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | Magenta Therapeutics, Inc. (US) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019113375-A2 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | Magenta Therapeutics, Inc. (US) | 2019-06-13 | — | — | WO | disclosed |