Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.51 |
| ▸ | HTR1A | P08908 | 7/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29966 | 0.85 | SLC6A2 (0.61) | SLC6A2HTR1ASLC6A3HTR2CLPAR1 | |
| SCHEMBL17123797 | 0.81 | SLC6A2 (0.57) | SLC6A2HTR1ASLC6A3HTR2CLPAR1 | |
| SCHEMBL9538522 | 0.79 | SLC6A2 (0.56) | SLC6A2HTR1ASLC6A3LPAR1LPAR5 | |
| SCHEMBL4699077 | 0.77 | PDE4A (0.41) | SLC6A2HTR1ASLC6A3SLC6A4PDE4A | |
| SCHEMBL16571016 | 0.76 | SLC6A2 (0.53) | SLC6A2HTR1ASLC6A3HTR2CLPAR1 | |
| SCHEMBL18186077 | 0.76 | SLC6A2 (0.53) | SLC6A2HTR1ASLC6A3HTR2CLPAR1 | |
| SCHEMBL12181083 | 0.76 | SLC6A2 (0.53) | SLC6A2HTR1ASLC6A3HTR2CLPAR1 | |
| SCHEMBL234010 | 0.76 | SLC6A2 (0.81) | SLC6A2HTR1ASLC6A3HTR2CSLC6A4 | |
| SCHEMBL2298389 | 0.76 | SLC6A2 (0.53) | SLC6A2HTR1ASLC6A3HTR2CLPAR1 | |
| SCHEMBL21047681 | 0.76 | MEN1 (0.47) | SLC6A2SLC6A3SLC6A4PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247990-B1 | Bicyclic fused pyridine compounds as inhibitors of TAM kinases | ARRAY BIOPHARMA INC (US) | 2022-02-15 | — | — | US | disclosed |
| WO-2019113190-A1 | BICYCLIC FUSED PYRIDINE COMPOUNDS AS INHIBITORS OF TAM KINASES | ARRAY BIOPHARMA INC. (US) | 2019-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11247990-B1 | Bicyclic fused pyridine compounds as inhibitors of TAM kinases | MAP3K1, MAP3K3, MAP3K2 | SLC6A2 3958/4885HTR1A 2149/4885SLC6A3 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.