Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.61 |
| ▸ | HTR1A | P08908 | 9/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17123797 | 0.91 | SLC6A2 (0.57) | SLC6A2HTR1ASLC6A3SLC6A4LPAR1 | |
| SCHEMBL18186077 | 0.90 | SLC6A2 (0.53) | SLC6A2HTR1ASLC6A3SLC6A4LPAR1 | |
| SCHEMBL16571016 | 0.90 | SLC6A2 (0.53) | SLC6A2HTR1ASLC6A3SLC6A4LPAR1 | |
| SCHEMBL9538522 | 0.90 | SLC6A2 (0.56) | SLC6A2HTR1ASLC6A3SLC6A4LPAR1 | |
| SCHEMBL12181083 | 0.86 | SLC6A2 (0.53) | SLC6A2HTR1ASLC6A3SLC6A4LPAR1 | |
| SCHEMBL234010 | 0.86 | SLC6A2 (0.81) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL2298389 | 0.86 | SLC6A2 (0.53) | SLC6A2HTR1ASLC6A3SLC6A4LPAR1 | |
| SCHEMBL24247168 | 0.86 | SLC6A2 (0.49) | SLC6A2HTR1ASLC6A3SLC6A4LPAR1 | |
| SCHEMBL24247269 | 0.86 | SLC6A2 (0.49) | SLC6A2HTR1ASLC6A3SLC6A4LPAR1 | |
| SCHEMBL21055229 | 0.85 | SLC6A2 (0.51) | SLC6A2HTR1ASLC6A3SLC6A4LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174556-A1 | COMPOUNDS AS PROTEIN KINASE INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-06-08 | — | — | US | disclosed |
| US-9241487-B2 | Pyrimidine derivatives and use thereof as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-26 | — | — | US | disclosed |
| US-9198429-B2 | Heterocyclic alkanol-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-9095136-B2 | 2-IODO imidazole-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| EP-2609088-B1 | 5-IODO-TRIAZOLE DERIVATIVES | BAYER IP GMBH (DE) | 2015-04-29 | — | — | EP | disclosed |
| US-8969248-B2 | 5-iodotriazole derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-03 | — | — | US | disclosed |
| US-20140336232-A1 | 2-IODO IMIDAZOLE-DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | BAYER INTELLCTUAL PROPERTY GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| US-20140031373-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| EP-2646418-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | Bayer Intellectual Property GmbH (DE) | 2013-10-09 | — | — | EP | disclosed |
| EP-2609088-A1 | 5-IODO-TRIAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-07-03 | — | — | EP | disclosed |
| US-20120220638-A1 | 5-Iodotriazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-08-30 | — | — | US | disclosed |
| WO-2012072547-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012025506-A1 | 5-IODO-TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336232-A1 | 2-IODO IMIDAZOLE-DERIVATIVES | CIP2A, ING2, AZI2 | SLC6A2 4614/4885HTR1A 3848/4885SLC6A3 4423/4885 |
| US-20140031373-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | TYMP, TYMS, UMPS | SLC6A2 4458/4885HTR1A 3588/4885SLC6A3 3862/4885 |
| US-20120220638-A1 | 5-Iodotriazole derivatives | INMT, IGFBP5, HDHD5 | SLC6A2 4205/4885HTR1A 2432/4885SLC6A3 3072/4885 |
| US-20230174556-A1 | COMPOUNDS AS PROTEIN KINASE INHIBITORS | PIK3CA, AKT1, PIK3CB | SLC6A2 4778/4885HTR1A 4211/4885SLC6A3 4708/4885 |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | ERG28, CBR3, MYB | SLC6A2 4853/4885HTR1A 3543/4885SLC6A3 4812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.