SCHEMBL21057134

SCHEMBL21057134

CC[C@H](Oc1ccc(Br)cc1F)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 9/20 0.49
PPARG P37231 7/20 0.49
SMN1; SMN2 Q16637 1/20 0.47
SLC6A4 P31645 1/20 0.46
FPR2 P25090 1/20 0.44
MAPT P10636 1/20 0.42
AAK1 Q2M2I8 2/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4817990 1.00 PPARA (0.49) PPARAPPARGSMN1; SMN2SLC6A4FPR2
SCHEMBL10516010 0.91 SMN1; SMN2 (0.46) PPARAPPARGSMN1; SMN2SLC6A4FPR2
SCHEMBL21057182 0.89 PPARG (0.48) PPARAPPARGSMN1; SMN2SLC6A4FPR2
SCHEMBL21057180 0.89 PPARG (0.48) PPARAPPARGSMN1; SMN2SLC6A4FPR2
SCHEMBL21057108 0.87 PPARA (0.50) PPARAPPARGSLC6A4FPR2AAK1
SCHEMBL21057105 0.87 PPARA (0.50) PPARAPPARGSLC6A4FPR2AAK1
SCHEMBL21057154 0.85 PPARA (0.49) PPARAPPARGSLC6A4FPR2AAK1
SCHEMBL21057151 0.85 PPARA (0.49) PPARAPPARGSLC6A4FPR2AAK1
SCHEMBL8935782 0.85 PPARA (0.52) PPARAPPARGSMN1; SMN2MAPTPTGDR2
SCHEMBL8935780 0.85 PPARA (0.52) PPARAPPARGSMN1; SMN2MAPTPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731200-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD Pharma A/S (DK) 2026-04-29 EP claimed
WO-2024261020-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD PHARMA A/S (DK) 2024-12-26 WO claimed
EP-3723745-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2020-10-21 EP claimed
CN-111587109-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-25 CN claimed
WO-2019115777-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO claimed
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS 2019-06-20 US claimed
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US claimed
EP-4731200-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD Pharma A/S (DK) 2026-04-29 EP disclosed
WO-2024261020-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD PHARMA A/S (DK) 2024-12-26 WO disclosed
EP-3723745-B1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2024-06-19 EP disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
US-11147788-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2021-10-19 US disclosed
EP-3723745-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2020-10-21 EP disclosed
CN-111587109-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-25 CN disclosed
WO-2019115777-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO disclosed
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS 2019-06-20 US disclosed
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730714-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 PPARA 3247/4885PPARG 3332/4885SMN1; SMN2 13/4885
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 PPARA 3247/4885PPARG 3332/4885SMN1; SMN2 13/4885
US-11147788-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 PPARA 3247/4885PPARG 3332/4885SMN1; SMN2 13/4885
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 PPARA 3247/4885PPARG 3332/4885SMN1; SMN2 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.