Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.52 |
| ▸ | PPARG | P37231 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935782 | 1.00 | PPARA (0.52) | PPARAPPARGSMN1; SMN2MAPTMEN1 | |
| SCHEMBL1566058 | 0.85 | PPARG (0.48) | PPARAPPARGMAPTMEN1HPGD | |
| SCHEMBL21057209 | 0.85 | PPARA (0.71) | PPARAPPARGSMN1; SMN2PTGDR2 | |
| SCHEMBL21057134 | 0.85 | PPARA (0.49) | PPARAPPARGSMN1; SMN2MAPTPTGDR2 | |
| SCHEMBL4817990 | 0.85 | PPARA (0.49) | PPARAPPARGSMN1; SMN2MAPTPTGDR2 | |
| SCHEMBL21057210 | 0.85 | PPARA (0.71) | PPARAPPARGSMN1; SMN2PTGDR2 | |
| SCHEMBL2103556 | 0.85 | PKM (0.54) | PPARAPPARGSMN1; SMN2MAPTPTGDR2 | |
| SCHEMBL11364459 | 0.85 | PPARA (0.50) | PPARAPPARGSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6234211 | 0.84 | PPARG (0.69) | PPARAPPARGSMN1; SMN2MAPTHPGD | |
| SCHEMBL8936023 | 0.84 | PPARG (0.69) | PPARAPPARGSMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |