Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.49 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21058255 | 0.93 | S1PR1 (0.48) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL21058237 | 0.85 | TAAR1 (0.54) | — | |
| SCHEMBL17351151 | 0.84 | SLC6A2 (0.52) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL27565318 | 0.84 | SLC6A2 (0.52) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| Hydrochloric Acid SCHEMBL5427418 | 0.83 | SLC6A2 (0.50) | S1PR1KCNH2SIGMAR1 | |
| Water SCHEMBL4443337 | 0.83 | SLC6A2 (0.50) | KCNH2SIGMAR1 | |
| SCHEMBL20343995 | 0.82 | SLC6A2 (0.44) | KCNH2SIGMAR1 | |
| SCHEMBL9466924 | 0.80 | TAAR1 (0.48) | S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL17493636 | 0.79 | CETP (0.47) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL19725599 | 0.79 | CETP (0.47) | S1PR1S1PR4S1PR3S1PR5TNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | THE UNIVERSITY OF TOLEDO (US) | 2020-12-15 | — | — | US | claimed |
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | THE UNIVERSITY OF TOLEDO (US) | 2019-06-20 | — | — | US | claimed |
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | THE UNIVERSITY OF TOLEDO (US) | 2020-12-15 | — | — | US | disclosed |
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | THE UNIVERSITY OF TOLEDO (US) | 2020-12-15 | — | — | US | disclosed |
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | THE UNIVERSITY OF TOLEDO (US) | 2019-06-20 | — | — | US | disclosed |
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | THE UNIVERSITY OF TOLEDO (US) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | CHKB, HRH3, PNMT | S1PR1 1464/4885S1PR4 993/4885S1PR3 1045/4885 |
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | CHKB, HRH3, PNMT | S1PR1 1616/4885S1PR4 1093/4885S1PR3 1171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.