Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210176 | 0.94 | ABL1 (0.33) | ABL1P2RX4PIK3C3 | |
| SCHEMBL212529 | 0.94 | ABL1 (0.33) | ABL1P2RX4PIK3C3 | |
| SCHEMBL209966 | 0.94 | CTSK (0.34) | ABL1P2RX4TDP1 | |
| SCHEMBL212049 | 0.93 | ABL1 (0.33) | ABL1 | |
| SCHEMBL4341222 | 0.92 | ABL1 (0.34) | ABL1P2RX4PIK3C3 | |
| SCHEMBL213676 | 0.92 | ABL1 (0.31) | ABL1P2RX4PIK3C3 | |
| SCHEMBL213942 | 0.90 | ABL1 (0.34) | ABL1P2RX4 | |
| SCHEMBL210973 | 0.90 | P2RX4 (0.32) | ABL1P2RX4 | |
| SCHEMBL210546 | 0.89 | CTSK (0.34) | ABL1P2RX4TDP1 | |
| SCHEMBL209633 | 0.89 | ABL1 (0.34) | ABL1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | claimed |
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |