Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.72 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986102 | 0.85 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3718236 | 0.84 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1KDM4EADORA1 | |
| SCHEMBL4643760 | 0.81 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1KMT2AMEN1SQOR | |
| SCHEMBL28351894 | 0.80 | KDM4E (0.64) | HSP90AA1HSP90AB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL24122900 | 0.80 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL5918453 | 0.77 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL21058449 | 0.77 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL31047268 | 0.77 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL10646200 | 0.77 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL385448 | 0.77 | IDO1 (0.48) | HSP90AA1HSP90AB1SMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190185456-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-06-20 | — | — | US | disclosed |
| CN-107759571-A | Inhibitors of influenza viruses replication and its application method and purposes | 广东东阳光药业有限公司 | 2018-03-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185456-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | POLRMT, EIF2AK2, POLM | HSP90AA1 2980/4885HSP90AB1 2531/4885KMT2A 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.