SCHEMBL2105887

SCHEMBL2105887

FC(F)(F)C(F)(F)C(F)(F)Sc1[c]cccc1-c1cccnc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.39
CYP2A6 P11509 5/20 0.37
CYP3A4 P08684 3/20 0.37
ALDH1A1 P00352 3/20 0.37
CYP1A2 P05177 1/20 0.37
SLC22A12 Q96S37 1/20 0.36
NPY5R Q15761 1/20 0.34
CYP2E1 P05181 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2B6 P20813 2/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
PTGS2 P35354 1/20 0.33
S1PR1 P21453 1/20 0.33
CYP11B1 P15538 1/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TDO2 P48775 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2105682 0.83
SCHEMBL4365990 0.71 CYP2A6 (0.48) PDK2CYP2A6CYP3A4ALDH1A1CYP1A2
SCHEMBL23071560 0.70 CYP2A6 (0.50) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL4287900 0.69 PDK2 (0.44) PDK2SLC22A12NPC1PTGS2RAB9A
SCHEMBL8879482 0.68 CYP2A6 (0.49) CYP2A6CYP3A4ALDH1A1CYP1A2NPY5R
SCHEMBL7952212 0.68 CYP2A6 (0.49) CYP2A6CYP3A4ALDH1A1CYP1A2NPC1
SCHEMBL28592408 0.67 CYP2A6 (0.47) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL7953803 0.65 MKNK1 (0.46) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL4289010 0.65 HSD17B1 (0.39) CYP3A4CYP2C9
SCHEMBL20541087 0.64 CYP2A6 (0.70) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163804-B2 Composition for preventing harmful organisms MITSUI CHEMICALS, INC. (JP) 2012-04-24 US disclosed