SCHEMBL2105910

SCHEMBL2105910

CCN(CC)C(Cl)=C(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 3/20 0.38
EHMT1 Q9H9B1 3/20 0.38
ABCB11 O95342 2/20 0.38
HTT P42858 2/20 0.38
GSDMD P57764 2/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA4 P22748 2/20 0.38
CA9 Q16790 2/20 0.38
CYP2E1 P05181 1/20 0.38
PTGS1 P23219 1/20 0.38
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 2/20 0.36
LMNA P02545 2/20 0.36
PHGDH O43175 2/20 0.36
MGLL Q99685 2/20 0.36
PLIN1 O60240 1/20 0.36
GMNN O75496 1/20 0.36
TRPA1 O75762 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11003801 0.76 EHMT2 (0.36) EHMT2EHMT1ABCB11HTTGSDMD
SCHEMBL3168181 0.71 EHMT2 (0.33) EHMT2EHMT1ABCB11HTTGSDMD
SCHEMBL2099385 0.71 EHMT2 (0.33) EHMT2EHMT1ABCB11HTTGSDMD
SCHEMBL2101421 0.71 EHMT2 (0.33) EHMT2EHMT1ABCB11HTTGSDMD
SCHEMBL3168188 0.71 EHMT2 (0.33) EHMT2EHMT1ABCB11HTTGSDMD
SCHEMBL134714 0.69
SCHEMBL26478834 0.69
SCHEMBL356069 0.69
SCHEMBL29114756 0.69
SCHEMBL11610645 0.67 ABCB11 (0.31) EHMT2EHMT1ABCB11HTTGSDMD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2023-11-23 US disclosed
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2023-09-19 US disclosed
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2021-07-29 US disclosed
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2021-05-04 US disclosed
US-10435385-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2019-10-08 US disclosed
US-20180134681-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2018-05-17 US disclosed
US-9920026-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2018-03-20 US disclosed
EP-1714958-B9 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE MITSUI CHEMICALS AGRO INC (JP) 2017-05-31 EP disclosed
EP-1714958-B1 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE MITSUI CHEMICALS AGRO INC (JP) 2016-12-21 EP disclosed
US-20160002198-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2016-01-07 US disclosed
EP-0054865-A1 Substituted 1-azolyl-butan-2-ones, their preparation and their application as fungicides as well as intermediates BAYER AG (DE) 1982-06-30 EP disclosed
EP-0044425-A2 Halogenated triazolylvinyl-keto and carbinol derivatives, process for their preparation and their use as fungicides and plant growth regulators BAYER AG (DE) 1982-01-27 EP disclosed
EP-0004303-B1 ACYLATED 1-AZOLYL-2-HYDROXY-BUTANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1982-01-13 EP disclosed
EP-0041671-A1 Substituted 3,3-dimethyl-butan-2-ones, process for their preparation and their use as intermediate products BAYER AG (DE) 1981-12-16 EP disclosed
US-4255434-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-03-10 US disclosed
US-4254132-A Combating fungi with 2-acyloxy-1-azolyl-3,3-dimethyl-2-phenoxy-butanes BAYER AKTIENGESELLSCHAFT (DE) 1981-03-03 US disclosed
US-4124707-A 7α-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their manufacture, their use as anti-inflammatory agents, and pharmaceutical formulations useful therefor SCHERING CORPORATION (US) 1978-11-07 US disclosed
US-4079054-A 7α-Halogeno-3-oxo-1,4-pregnadiene-21,17β-carbolactones and related compounds SCHERING CORPORATION (US) 1978-03-14 US disclosed
US-3972906-A Novel - 11-substituted steroids of the estrane series AKZONA INCORPORATED (US) 1976-08-03 US disclosed
US-3933799-A HORMONES GLAXO LABORATORIES LIMITED (EN) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180134681-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE CYP1A1, CYP4B1, CYP2E1 EHMT2 3093/4885EHMT1 2815/4885ABCB11 1342/4885
US-20160002198-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE CYP1A1, CYP4B1, CYP2E1 EHMT2 3093/4885EHMT1 2815/4885ABCB11 1342/4885
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 EHMT2 1189/4885EHMT1 708/4885ABCB11 2100/4885
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 EHMT2 1189/4885EHMT1 708/4885ABCB11 2100/4885
US-10435385-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 EHMT2 1189/4885EHMT1 708/4885ABCB11 2100/4885
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 EHMT2 1189/4885EHMT1 708/4885ABCB11 2100/4885
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 EHMT2 1189/4885EHMT1 708/4885ABCB11 2100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.