Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 6/20 | 0.79 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.64 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.64 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.64 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | TSPO | P30536 | 1/20 | 0.64 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.54 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30073256 | 1.00 | PLA2G4A (0.79) | PLA2G4ATP53CYP1A2CYP2D6MAPT | |
| SCHEMBL3765894 | 1.00 | PLA2G4A (0.79) | PLA2G4ATP53CYP1A2CYP2D6MAPT | |
| SCHEMBL13393777 | 0.92 | PLA2G4A (0.67) | PLA2G4ATP53CYP1A2CYP2D6MAPT | |
| SCHEMBL16085651 | 0.89 | PLA2G4A (0.66) | PLA2G4ATP53CYP1A2CYP2D6MAPT | |
| SCHEMBL12451633 | 0.88 | PLA2G4A (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL31620245 | 0.88 | PLA2G4A (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL30649214 | 0.88 | PLA2G4A (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL31620248 | 0.88 | PLA2G4A (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL31620246 | 0.88 | PLA2G4A (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL14090319 | 0.88 | PLA2G4A (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805761-A1 | COMPOSITION FOR DIAGNOSING DISEASES ASSOCIATED WITH COX2 OVEREXPRESSION AND SCREENING METHOD THEREFOR | Kyungpook National University Industry-Academic Cooperation Foundation (KR) | 2021-04-14 | — | — | EP | disclosed |
| US-20190183910-A1 | ENHANCING DNA REPAIR AND PREVENTING AGING AND ITS CONSEQUENCES IN REPRODUCTIVE AND OTHER CELLS | OKTAY, KUTLUK (US) | 2019-06-20 | — | — | US | disclosed |