⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555175 | 1.00 | — | — | |
| SCHEMBL25176024 | 1.00 | — | — | |
| SCHEMBL2228489 | 0.88 | PTPN11 (0.32) | — | |
| SCHEMBL932416 | 0.86 | GNAI3 (0.39) | — | |
| Hydrochloric Acid SCHEMBL15819855 | 0.84 | GNAI3 (0.42) | — | |
| SCHEMBL3656394 | 0.81 | — | — | |
| SCHEMBL6277605 | 0.80 | — | — | |
| SCHEMBL25188572 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL21274192 | 0.79 | — | — | |
| SCHEMBL2560134 | 0.79 | HRH2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3724196-A1 | SUBSTITUTED AZETIDINE DIHYDROTHIENOPYRIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | Leo Pharma A/S (DK) | 2020-10-21 | — | — | EP | disclosed |
| WO-2019115776-A1 | SUBSTITUTED AZETIDINE DIHYDROTHIENOPYRIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2019-06-20 | — | — | WO | disclosed |