Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21098084 | 1.00 | CTSK (0.57) | CTSKCA1CA2HSD11B1CYP2C9 | |
| SCHEMBL21098058 | 1.00 | CTSK (0.57) | CTSKCA1CA2HSD11B1CYP2C9 | |
| SCHEMBL3448253 | 0.89 | CTSK (0.52) | CTSKCA1CA2HSD11B1CYP2C9 | |
| SCHEMBL3448248 | 0.89 | CTSK (0.52) | CTSKCA1CA2HSD11B1CYP2C9 | |
| SCHEMBL10293867 | 0.89 | CTSK (0.57) | CTSKCA1CA2HSD11B1CYP2C9 | |
| SCHEMBL8256718 | 0.89 | CTSK (0.57) | CTSKCA1CA2HSD11B1CYP2C9 | |
| SCHEMBL5847911 | 0.89 | CTSK (0.57) | CTSKCA1CA2HSD11B1CYP2C9 | |
| SCHEMBL10006308 | 0.89 | CTSK (0.57) | CTSKCA1CA2HSD11B1CYP2C9 | |
| SCHEMBL3942865 | 0.85 | CTSK (0.59) | CTSKCA1CA2HSD11B1CYP2C9 | |
| SCHEMBL12321230 | 0.85 | CTSK (0.59) | CTSKCA1CA2HSD11B1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |